Speciation 98: Abstracts

JESS computer modelling is used to produce biokinetic models of the gastrointestinal tract, for the radiation dose from internally deposited radionuclides to be calculated. Estimations of the interactions of Nd, Gd, Eu, Am and Cm with all the metal binding species present in the different compartments of the gastrointestinal tract i.e. mouth, stomach and small intestine, have been made. However, the results of the lanthanide and actinide simulations in the small intestine compartment i.e. bile and pancreatic fluid, over a pH range of pH = 5.0 to 9.0 and at a temperature of 37 ^oC, will be discussed. The development of the models and these initial validation results for the use of Nd, Gd and Eu as possible surrogates for Am and Cm, will be presented and discussed. From these studies it appears that the use of Nd, Gd or Eu as surrogates for Am or Cm in bile and pancreatic fluid, although showing some similarities, are not conclusive. However, further development of the speciation modelling, incorporating some new data, is in process to confirm these findings.

Back to the list of abstracts