Back to the list of abstracts
Speciation 98: Abstracts
Hajnalka Csóka1, Gareth Bell2 and Etelka Farkas1
1 Department of Inorganic and Analitical Chemistry,
Lajos Kossuth University, H-4010, Debrecen, Hungary;
2 Department of Chemistry, University College Dublin,
Belfield, Dublin 4, Republic of Ireland
Over the past few decades considerable experimental evidence has indicated that the imidazole group of histidine may serve a number of important biological functions. Considering this role of histidine and the biological activities of compounds containing hydroxamic group, it seemed worthwhile to investigate the coordination properties of histidinehydroxamic acid derivative.
The result of chelation of histidinehydroxamic acid on copper(II) has already been reported. The binding is realized through the imidazole nitrogen and amino nitrogen for the species formed in low pH and through amino nitrogen and hydroxamate N for the species formed in the 3-6 pH region.
In our work we have investigated the complex formation between histidinehydroxamic acid and the essential metal ion Mo(VI) by means of potentiometric, spectroscopic, n.m.r. and IR methods. Furthermore potentiometric and n.m.r. methods were used to establish the coordination equilibria in the previously not studied Al(III)-histidinehydroxamic acid system.
Since in these cases considerable coordination of the imidazole nitrogen has not been observed, but previous studies of the Fe(III) -histidinehydroxamic acid system assumed first of all N-coordinations in the complexes, we performed a new study of this equilibria using potentiometric, spectroscopic and n.m.r. methods.
Our results will be presented on the poster.
