Göndös, György

reader (associate professor)

Department of Organic Chemistry, József Attila University, Dóm tér 8, H-6720 Szeged,

Hungary, e-mail: gondos@chem.u-szeged.hu fax: (+36)62-425768

Born: February 15, 1939

Education: undergraduate studies: 1957-1962, József Attila University, Szeged

Ph.D. degree: 1977, Hungarian Academy of Sciences

Experience: 1962-1978: assistant professor

1978-: reader (associate professor)

Fellowship: Post doctoral fellowship with Prof. Dr. J. C. Orr, Faculty of Medicine, Memorial University of Newfoundland, St. John^,s, Canada, 1980-1981 (17 months).

Research associate position with Prof. Dr. J. G. Fodor, Faculty of Medicine Memorial

University of Newfoundland, St. John^,s, Canada, 1989-1993 (3.5 years).

Visiting scientist position with Prof. Dr. L. Paszner, Department of Wood Science,

Faculty of Forestry, University of British Columbia, Vancouver, B.C., Canada,

1996-1997 (13 month).

Research interest:

Areas of special interest and accomplishment in discipline:

1. Asymmetric hydrogenation of steroid 3-, 17- and 20-ketones catalyzed by metal

complexes with chiral ligands and chiral modified heterogeneous metal catalysts

1. Studiyng the Friedel-Crafts alkylation reaktions of estrogens by intercalar catalysts

2. Synthesis of pharmacologically active nitrogen-contained heterocyclic compounds.

Hydrogenolysis of C-N bond in nitrogen-contained saturated heterocyclic

compounds

1. Selective synthesis and structure analysis of 8,13-diazasteroids and their D-homo

derivatives.

1. Stereospecific synthesis and conformation studies of 1,3-difunctional alicyclic

systems.

1. Determination and evaluation of beta-thromboglobulin by using radioimmunoassay

method.

Selected publications:

Gy. Göndös, L. K. Láng, A. Szeghy, Gy. Dombi, G. Bernáth: Stereochemical studies

Part 31. Ring closure reactionof cis- and trans-2-(bromomethyl)cycloalkylamines. J. C. S. Perkin 1. 1770 (1979)

Gy. Göndös, J. C. Orr: Stereoselective and regioselective reduction of steroid ketones by potassium tri(R,S-s-butyl)borohydride, J. C. S. Chem. Commun., 1239 (1982).

Gy. Göndös, J. C. Orr: Reduction of steroid 17-ketones by enantiomeric chiral reducing agents. J. C. S . Chem. Commun., 1238 (1982).

Gy. Göndös, L. C. McGirr, C. R. Jablonski, W. Snedden, J. C. Orr: The reduction of steroid 2 -fluoro-4-en-3-ones. J. Org. Chem. 53, 3057 (1988).

Gy. Göndös, I. Szécsényi, Gy. Dombi: An efficient synthesis of cis- and trans-2-aminocyclohexanecarboxamides and their N-substituted derivatives. Liebigs Ann. Chem., 591 (1991).

Gy. Göndös, Gy. Wittmann, M. Bartók, J. C. Orr: Chiral hydrogenation of estrone-3-methyl ether on modified Raney nickel catalysts. Steroids, 58, 533 (1993).

Gy. Göndös, J. C. Orr: Borane reduction of steroid 20-ketone group in the presence of various chiral -amino alcohols. Liebigs Ann. Chem., 581 (1993).

Gy. Göndös, L. Gera, Gy. Dombi, G. Bernáth: 2-Substituted hexahydroacylanthra-nils: Synthesis and selective reactions with amines.Monatshefte für Chemie, 127, 1167 (1996)

Gy. Göndös, I. Kapocsi: Friedel-Crafts reaction with FeCl₃-graphite. J. Phys. Chem. Solids, 57, 855 (1996).

Gy. Göndös, L. Gera, G. Tóth, A. Kálmán, J. Bridson: Synthesis and stereo-chemistry of 8,13-diaza-2,3-dimethoxygona-1,3,5(10),9(11)-tetraen-12-one and

D-homo derivatives. Steroids, 63, 375 (1998).