Research profile
It
bears
a
great
impact
to
reveal
the
different
behavior
of
enantiomers
of
pharmaceutical
compounds,
since
one
of
the
enantiomers
may
have
a
positive
effect
thanks
to
its
biological
activity,
while
the
other
enantiomer
may
be
inactive,
or
it
may
have
some
unwanted
or
even
toxic
effect.
As
opposed
to
the
past,
nowadays
enantiomerically
pure
compounds
are
preferred
in
the
pharmaceutical
industry.
The
separation
of
enantiomers
having
biological
and/or
pharmaceutical
interest is an important task in modern analytical chemistry.
The
deeper
understanding
of
the
mechanistic
details
of
chiral
recognition
is
essential
for
designing
of
enantioselective
separation
methods
and
developing
new
stationary
phases.
Through
the
determination
of
the
chromatographic
parameters
of
the
applied
model
compounds,
we
investigate
the
effects
of
the
composition
of
the
mobile
phase
and
the
nature
and
concentration
of
different
additives
on
the
separation.
Investigation
of
the
effect
of
the
temperature
on
the
chromatographic
parameters
and
study
the
relationship
between
the
physico-chemical
parameters
and
the
chromatographic
characteristics
is
also
an
important
issue.
In
our
investigations
focus
is
put
on
the
high-
and
ultrahigh-
performance liquid chromatography-based methodologies.
As
a
further
aim
the
development
of
new
analytical
methods
for
the
determination
of
highly
important
compounds
related to life sciences (e.g. kynurenic acid and its analogs) from biological systems can be mentioned.
Frissítve: 2023.02.05.
University of Szeged, Department of Inorganic and Analytical Chemistry, H-6720 Szeged, Dóm tér 7.
Scientometric data:
Publications in scientific journals: 115
Conference papers: 11
Books, book chapters: 16
Patent: 1
Educational works: 1
Conference presentations: 160
Impact factors: 330
Independent citations: 2121
H-index: 28
link to MTMT database
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